In the transaction window, is there any way I can sort by debit or credit amounts by clicking on the columns headings. The advanced filter works OK but doesn't include the amount fields.
Am I able to create a report or configure a report and then save it as a separate report?
No you cannot sort by amount. One work-around is to export your data (click menu File > Export Data), then open the transactions.csv file in Excel. You can then sort by the amount in Excel.
You cannot save the report configuration, except for the Profit and Loss report which automatically saves the configuration and uses it next time.